VUuniversityA recent study reflected that the brain activity networks of those with Alzheimer’s disease (AD) was more random and unstructured, which was a deviation from the optimal balance between local specialization and global integration seen in individuals without dementia. The study was conducted by applying the network mapping technique described in the open access journal BMC Neuroscience to the EEG data obtained from patients with AD and frontotemporal lobar degeneration (FTLD, a less common type of dementia with more prominent behavioral symptoms). The researchers claim that these results support the ‘disconnection syndrome’ hypothesis of AD; deterioration of cognition due to loss of functional connectivity and organization.