Tamoxifen may ease bipolar mania symptoms
Tamoxifen, a drug that is typically used to treat breast cancer, may help to decrease symptoms of mania in bipolar patients, according to a new report from Turkey. The three-week trial showed that about 50% of manic patients who took the drug improved during treatment, as compared to just 5% of placebo-treated patients. Patients with bipolar disorder exhibit mania, an abnormally elevated mood that may be characterized by impulsive behavior and higher energy and activity levels.
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understandingbi-polar on 25 Mar 2008 at 11:22 am #
This new advice is based on an analysis of 199 studies involving nearly 44,000 patients. The analysis found that the risk of suicidal thinking, behavior, and/ or attempts was quite low— less than 1 percent in both people who took one of the drugs and in those who took a placebo pill. However, among those who took one of the drugs, the risk of suicidal thoughts and attempts was twice that of those who took placebos— 0. 43 percent compared with 0. 22 percent. The FDA reported that four people who took one of…